A review on the recent application of ketamine in the management of anesthesia, pain, and health care total information in 2020

Mabel R. Acton
Ketamine: A Review of an Established Yet Often Underappreciated Medication  - Anesthesia Patient Safety Foundation


Ketamine is considered as a promising drug for many clinical applications even after five decades since its discovery. Ketamine is a dissociative anesthetic agent with a variety of pharmacological effects from anesthetic induction and maintenance to analgesic and sedative depending on the consuming dose. It can be used solely or in combination with other co-adjuvant drugs, increasing their efficacy. Many therapeutic properties of ketamine have been attributed to its antagonism mechanism to the N-Methyl-D-aspartate receptor. Identifying new properties of ketamine such as neuroprotective, anti-inflammatory, and antitumor effects, on one hand, and taking advantage of subanesthetic regimens of ketamine, on … Read More

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